Funded Translational Research Accelerator Grant Projects
Since 2019, GOSH Charity has been proud to partner with medical research charity LifeArc to deliver an ambitious funding scheme specifically supporting translational research at Great Ormond Street Hospital and the UCL Great Ormond Street Institute of Child Health that is focused on addressing medical needs for rare disease patients.
Below is a list of the projects funded through this grant scheme. If you have any questions about any of the projects, get in touch with the GOSH Charity Grants Team.
GOSH Charity and LifeArc Translational Research Accelerator Grants 2023
| Lead Investigator | Institution | Project Title | Total |
|---|---|---|---|
| Dr Stavros Loukogeorgakis | UCL Great Ormond Street Institute of Child Health | In Utero Cell Therapy for Alpha Thalassaemia | £334,216 |
| Prof Paolo De Coppi | University College London | TRANSLATE: Tissue-engineeRed grAft for the treatmeNt of OeSophageaL ATrEsia - optimisation of GMP-compatible conditions | £402,035 |
| Prof John Anderson | UCL Great Ormond Street Institute of Child Health | Generation of an IMiD drug responsive on-switch CAR-T cell platform for enhancedfunction in childhood solid cancers | £212,285 |
GOSH Charity and LifeArc Translational Research Accelerator Grants 2021
| Investigator | Institution | Project Title | Total |
|---|---|---|---|
| Prof David Long | UCL Great Ormond Street Institute of Child Health | Nanocomplex therapy for childhood kidney disease | £193,851 |
| Prof Jane Sowden | UCL Great Ormond Street Institute of Child Health | Engineering a cone-rich retinal cell patch to treat COD/CORD | £359,160 |
| Mr Martin Tisdall | UCL Great Ormond Street Institute of Child Health | The CADET Trial | £414,694 |
| Dr John Counsell | UCL Division of Surgery and Interventional Science | Preclinical validation of liver gene therapy for Maple Syrup Urine Disease | £336,385 |
GOSH Charity and LifeArc Translational Research Accelerator Grants 2019
| Lead Investigator | Institution | Project Title | Total |
|---|---|---|---|
| Dr Alessia Cavazza | UCL Great Ormond Street Institute of Child Health | Pre-clinical studies for a stem cell gene editing platform to treat primary immunodeficiencies | £249,734.35 |
| Prof Manju Kurian | UCL Great Ormond Street Institute of Child Health | A Phase II Study of a Novel Vitamin Metabolite (CoA-Z) for Pantothenate Kinase Associated Neurodegeneration (PKAN) | £414,842.00 |
| Dr Karin Straathof | UCL Great Ormond Street Institute of Child Health | IL13RA2-targeted T-cell therapy for paediatric high-grade gliomas | £273,702.81 |